BDBM50070324 CHEMBL3408252

SMILES C[C@@H](Nc1cc(F)cc(Cl)c1)c1cc(cc2c1oc(cc2=O)N1CCOCC1)C(=O)N(C)C

InChI Key InChIKey=AVJHOQVVSKUYKV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50070324   

LigandPNGBDBM50070324(CHEMBL3408252)
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant PI3Kgamma using PIP2 by Kinase-Glo Plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed
LigandPNGBDBM50070324(CHEMBL3408252)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant PI3Kdelta using PIP2 by Kinase-Glo Plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed
LigandPNGBDBM50070324(CHEMBL3408252)
Affinity DataIC50: 1nMAssay Description:Inhibition of PI3Kbeta in PTEN-null human MDA-MB-468 cells assessed as inhibition of Akt phosphorylation after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed
LigandPNGBDBM50070324(CHEMBL3408252)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant PI3Kbeta using PIP2 by Kinase-Glo Plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed
LigandPNGBDBM50070324(CHEMBL3408252)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant PI3Kalpha using PIP2 by Kinase-Glo Plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed