BDBM50070181 1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR)-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carbonyl)-urea::CHEMBL14022

SMILES CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1

InChI Key InChIKey=XEMCUJCVRDSIHH-UHFFFAOYSA-N

Data  1 KI  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50070181   

TargetD(1A) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataIC50: 850nMAssay Description:Displacement of [3H]SCH-23390 from D1 receptor in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataIC50: 310nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]spiroperidol from D2 receptor in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human 5-HT2B receptor transfected in CHO cell assessed as IP1 production incubated for 30 mins measured by HTRF detection methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataIC50: 2.55E+3nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataIC50: 280nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataIC50: 1.27E+3nMAssay Description:Displacement of [3H]yohimbine from Alpha-2 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50070181(1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [125I](+/-)DOI from human 5-HT2B receptor transfected in CHO cell membrane after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed