BDBM50069697 CHEMBL2356172

SMILES CC(C)NC(=O)Nc1ccc2O[C@@H](CN(C)S(=O)(=O)c3ccc(Cl)cc3)[C@H](C)CN([C@H](C)CO)C(=O)c2c1

InChI Key InChIKey=NMFHWISFZINRTB-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50069697   

TargetScavenger receptor class B member 1(Mouse)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50069697(CHEMBL2356172)
Affinity DataEC50:  400nMAssay Description:Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of binding of ALexa-488-labeled HDL particles to cells after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetScavenger receptor class B member 1(Mouse)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50069697(CHEMBL2356172)
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetScavenger receptor class B member 1(Mouse)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50069697(CHEMBL2356172)
Affinity DataIC50: 250nMAssay Description:Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of [3H]cholesteryl ester uptake into cells after 2 to 3 hrs by liquid sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetScavenger receptor class B member 1(Mouse)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50069697(CHEMBL2356172)
Affinity DataIC50: 250nMAssay Description:Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in uptake of [3H]CE from [3H]CE-HDL by by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed