BDBM50069174 Boronate Ester analogue::CHEMBL317682::N-[(5-Amino-1-dihydroxyboranyl-pentylcarbamoyl)-methyl]-N-methyl-3-phenyl-propionamide

SMILES CN(CC(=O)N[C@@H](CCCCN)B(O)O)C(=O)CCc1ccccc1

InChI Key InChIKey=RIUCWNRPWWTWOU-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50069174   

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069174(Boronate Ester analogue | N-[(5-Amino-1-dihydroxyb...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069174(Boronate Ester analogue | N-[(5-Amino-1-dihydroxyb...)
Affinity DataKi:  1.70nMAssay Description:In vitro for inhibition of thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50069174(Boronate Ester analogue | N-[(5-Amino-1-dihydroxyb...)
Affinity DataKi:  2.80nMAssay Description:Compound was tested in vitro for inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProthrombin(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50069174(Boronate Ester analogue | N-[(5-Amino-1-dihydroxyb...)
Affinity DataKi:  150nMAssay Description:Concentration necessary to double time for clot formation induced by bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50069174(Boronate Ester analogue | N-[(5-Amino-1-dihydroxyb...)
Affinity DataKi:  250nMAssay Description:In vitro for inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetTissue-type plasminogen activator(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50069174(Boronate Ester analogue | N-[(5-Amino-1-dihydroxyb...)
Affinity DataKi:  3.80E+3nMAssay Description:Compound was tested in vitro for inhibition of tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article