BDBM50068837 1-(3-{[5-Carbamoyl-2,6-dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3-carbonyl]-amino}-propyl)-4-phenyl-piperidine-4-carboxylic acid 2-hydroxy-ethyl ester::CHEMBL356623

SMILES CC1=NC(C)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(C(=O)OCCO)c1ccccc1

InChI Key InChIKey=GYYVAEHNOBJARP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50068837   

TargetAlpha-1A adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068837(1-(3-{[5-Carbamoyl-2,6-dimethyl-4-(4-nitro-phenyl)...)
Affinity DataKi:  9.05nMAssay Description:Binding affinity was determined for the alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068837(1-(3-{[5-Carbamoyl-2,6-dimethyl-4-(4-nitro-phenyl)...)
Affinity DataKi:  5.50E+3nMAssay Description:Binding affinity was determined for the alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068837(1-(3-{[5-Carbamoyl-2,6-dimethyl-4-(4-nitro-phenyl)...)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity was determined for the alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed