BDBM50068832 2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-methylamide 5-{[3-(4-phenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL358253

SMILES CNC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=UVICRDSFJQQDJY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50068832   

TargetAlpha-1A adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068832(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  6.17nMAssay Description:Binding affinity was determined for the alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068832(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  6.20nMAssay Description:Binding affinity to Homo sapiens (human) alpha1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetAlpha-1B adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068832(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  215nMAssay Description:Binding affinity was determined for the alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068832(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  630nMAssay Description:Binding affinity was determined for the alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed