BDBM50067892 4-Bromophenyl-boronic acid::4-bromo phenyl boronic acid::4-bromophenyl boronic acid::4-bromophenylboronic acid::Boronic acid derivative::CHEMBL20866

SMILES OB(O)c1ccc(Br)cc1

InChI Key InChIKey=QBLFZIBJXUQVRF-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50067892   

TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067892(4-bromo phenyl boronic acid | 4-bromophenyl boroni...)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibitory activity against Escherichia coli AmpC beta-lactamase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50067892(4-bromo phenyl boronic acid | 4-bromophenyl boroni...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSubtilisin BL(Bacillus lentus)
TBA

Curated by ChEMBL
LigandPNGBDBM50067892(4-bromo phenyl boronic acid | 4-bromophenyl boroni...)
Affinity DataKi:  1.00E+4nMAssay Description:Competitive inhibition of Subtilisin BL M222S-mutated enzyme from Bacillus lentusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50067892(4-bromo phenyl boronic acid | 4-bromophenyl boroni...)
Affinity DataKi:  1.17E+4nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase(Yeast)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50067892(4-bromo phenyl boronic acid | 4-bromophenyl boroni...)
Affinity DataKi:  1.59E+4nMAssay Description:Inhibition of Candida albicans recombinant Carbonic anhydrase pre-incubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSubtilisin BL(Bacillus lentus)
TBA

Curated by ChEMBL
LigandPNGBDBM50067892(4-bromo phenyl boronic acid | 4-bromophenyl boroni...)
Affinity DataKi:  2.30E+4nMAssay Description:Competitive inhibition of Subtilisin BL wild type enzyme from Bacillus lentusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSubtilisin Carlsberg(Bacillus licheniformis)
TBA

Curated by ChEMBL
LigandPNGBDBM50067892(4-bromo phenyl boronic acid | 4-bromophenyl boroni...)
Affinity DataKi:  2.30E+4nMAssay Description:Competitive inhibition of Subtilisin Carlsberg enzyme from Bacillus lentusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSubtilisin BL(Bacillus lentus)
TBA

Curated by ChEMBL
LigandPNGBDBM50067892(4-bromo phenyl boronic acid | 4-bromophenyl boroni...)
Affinity DataKi:  2.30E+4nMAssay Description:Competitive inhibition of Subtilisin BL M222C-mutated enzyme from Bacillus lentusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-lactamase TEM(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50067892(4-bromo phenyl boronic acid | 4-bromophenyl boroni...)
Affinity DataKi:  2.80E+4nMAssay Description:Inhibitory constant was determined against class A RTEM-1 Beta-lactamase from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetUrease(Soybean)
Banaras Hindu University

LigandPNGBDBM50067892(4-bromo phenyl boronic acid | 4-bromophenyl boroni...)
Affinity DataKi:  2.20E+5nM ΔG°:  -5.19kcal/molepH: 7.0 T: 2°CAssay Description:The inhibition studies of soybean urease were initiated with boric acid and boronic acids (butylboronic acid, 4-bromophenylboronic acid, and phenylbo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed