BDBM50067050 CHEMBL336630::Sodium; (1S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-2,6-diaza-bicyclo[3.2.0]heptane-6-sulfonate

SMILES [O-]S(=O)(=O)N1[C@@H]2CCN([C@@H]2C1=O)C(=O)NC1CCNCC1

InChI Key InChIKey=RCBJACYFANFNGP-UHFFFAOYSA-M

Data  2 IC50  2 Koff  2 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50067050   

TargetBeta-lactamase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067050(Sodium; (1S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-...)
Affinity DataKon:  0.00120M-1s-1Assay Description:Deacylation of 18SH Beta-lactamase of Pseudomonas aeruginosaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067050(Sodium; (1S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-...)
Affinity DataIC50: 39nMAssay Description:Inhibition of Pseudomonas aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067050(Sodium; (1S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-...)
Affinity DataKon:  0.00120M-1s-1 Koff:  1.5s-1Assay Description:Deacylation of 18SH Beta-lactamase of Pseudomonas aeruginosaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067050(Sodium; (1S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-...)
Affinity DataKoff:  1.5s-1Assay Description:Acylation of Pseudomonas aeruginosa 18SH Beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067050(Sodium; (1S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Escherichia coli TEM-3 Beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed