BDBM50067029 2-(3,4-Dihydroxy-benzylidene)-indan-1-one::2-[1-(3,4-Dihydroxy-phenyl)-meth-(E)-ylidene]-indan-1-one::CHEMBL126625

SMILES Oc1ccc(\C=C2/Cc3ccccc3C2=O)cc1O

InChI Key InChIKey=PPOMQCAGVJQMEO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50067029   

TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50067029(2-(3,4-Dihydroxy-benzylidene)-indan-1-one | 2-[1-(...)
Affinity DataIC50: 8.60E+4nMAssay Description:Compound concentration required to reduce HIV-1 Integrase 3'-processing activity by 50%More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50067029(2-(3,4-Dihydroxy-benzylidene)-indan-1-one | 2-[1-(...)
Affinity DataIC50: 8.51E+4nMAssay Description:Inhibitory activity against HIV-1 Integrase (HIV-1-IN)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase 17B(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50067029(2-(3,4-Dihydroxy-benzylidene)-indan-1-one | 2-[1-(...)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of recombinant GST-tagged DRAK2 (unknown origin) autophosphorylation after 2 hrs by ADP-glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Pecs

Curated by ChEMBL
LigandPNGBDBM50067029(2-(3,4-Dihydroxy-benzylidene)-indan-1-one | 2-[1-(...)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human recombinant MIF ketonase activity using phenylpyruvate as substrateMore data for this Ligand-Target Pair
In DepthDetails
PubMed