BDBM50067027 2,6-Bis-(3,4-dihydroxy-benzylidene)-cyclohexanone::2,6-Bis-[1-(3,4-dihydroxy-phenyl)-meth-(E)-ylidene]-cyclohexanone::2,6-bis(3,4-dihydroxybenzylidene)cyclohexanone::CHEMBL129148

SMILES Oc1ccc(\C=C2/CCC\C(=C/c3ccc(O)c(O)c3)C2=O)cc1O

InChI Key InChIKey=JZODVJPLOFJTJZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50067027   

TargetHistone acetyltransferase p300(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50067027(2,6-bis(3,4-dihydroxybenzylidene)cyclohexanone | 2...)
Affinity DataIC50: 2.33E+5nMAssay Description:Inhibition of GST-p300 HAT assessed as histone acetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50067027(2,6-bis(3,4-dihydroxybenzylidene)cyclohexanone | 2...)
Affinity DataIC50: 900nMAssay Description:Compound concentration required to reduce HIV-1 Integrase 3'-processing activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50067027(2,6-bis(3,4-dihydroxybenzylidene)cyclohexanone | 2...)
Affinity DataIC50: 891nMAssay Description:Inhibitory activity against HIV-1 Integrase (HIV-1-IN)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed