BDBM50066998 (3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrole-4-carboxylic acid ethyl ester::CHEMBL127027

SMILES CCOC(=O)N1CC[C@@H]2OC(=O)[C@H](CC=C)C12

InChI Key InChIKey=HVBZENRYJFPJCR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50066998   

TargetCathepsin G(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066998((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50: 3.60E+3nMAssay Description:The compound was tested for inhibition of cathepsin G with a pre-incubation time of 15 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066998((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50: 69nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a pre-incubation time of 15 min.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066998((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50: 4.00E+3nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a pre-incubation time of 15 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066998((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50: 2.00E+5nMAssay Description:The compound was tested for inhibition of thrombin with a pre-incubation time of 15 min.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed