BDBM50066996 (3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrole-4-carboxylic acid benzyl ester::CHEMBL125796

SMILES C=CC[C@H]1C2[C@H](CCN2C(=O)OCc2ccccc2)OC1=O

InChI Key InChIKey=AIOPERPCMDNFTR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50066996   

TargetNeutrophil elastase(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066996((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50: 1.28E+4nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a pre-incubation time of 0 min.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066996((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50: 74nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a pre-incubation time of 40 min.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066996((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50: 4.86E+3nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a pre-incubation time of 15 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066996((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50: 4.46E+4nMAssay Description:The compound was tested for inhibition of thrombin with a pre-incubation time of 15 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin G(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50066996((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50: 6.70E+4nMAssay Description:The compound was tested for inhibition of cathepsin G with a pre-incubation time of 15 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed