BDBM50066960 CHEMBL33700::N-(2-(5-methoxy-1-methyl-1H-indol-3-yl)ethyl)acetamide::N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-acetamide

SMILES COc1ccc2n(C)cc(CCNC(C)=O)c2c1

InChI Key InChIKey=GSMWHFKFNGUYRN-UHFFFAOYSA-N

Data  7 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50066960   

TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50066960(N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-ace...)
Affinity DataIC50: 2.82nMAssay Description:Displacement of [125I]iodomelatonin from MT3/QR2 melatonin binding site expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50066960(N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-ace...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of QR2 (unknown origin) using MTT and NMeH as substratesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50066960(N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-ace...)
Affinity DataIC50: 26nMAssay Description:inhibitory concentration against Melatonin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50066960(N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-ace...)
Affinity DataKi:  1.70nMAssay Description:Binding Affinity (pKi) towards human Melatonin receptor type 1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50066960(N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-ace...)
Affinity DataKi:  2.20nMAssay Description:Binding Affinity (pKi) towards human Melatonin receptor type 1AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50066960(N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-ace...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of 2-[125I]iodomelatonin binding to human Melatonin receptor type 1A expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50066960(N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-ace...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of 2-[125I]iodomelatonin binding to Melatonin receptor 3 (MT3) of Syrian hamster brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50066960(N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-ace...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of 2-[125I]iodomelatonin binding to human Melatonin receptor type 1B expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50066960(N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-ace...)
Affinity DataKi:  6.70nMAssay Description:Binding affinity for Melatonin receptor using 2-[125I]iodomelatonin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1C(Chicken)TBA
LigandPNGBDBM50066960(N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-ace...)
Affinity DataKi:  254nMAssay Description:Binding affinity towards melatonin receptor was determined using 2-[125I]iodomelatonin as radioligand in chick brain membranesMore data for this Ligand-Target Pair
In DepthDetails