BDBM50066481 (S)-2-Acetylamino-N-[(5S,11R,14S,17R,19aS)-17-cyclohexylmethyl-11-(3-guanidino-propyl)-14-(1H-indol-3-ylmethyl)-4,10,13,16,19-pentaoxo-icosahydro-3a,9,12,15,18-pentaaza-cyclopentacyclooctadecen-5-yl]-3-phenyl-propionamide::CHEMBL115478

SMILES CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCNC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@@H]2CCCN2C1=O

InChI Key InChIKey=YOKBGCTZYPOSQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066481   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50066481((S)-2-Acetylamino-N-[(5S,11R,14S,17R,19aS)-17-cycl...)
Affinity DataIC50: 12nMAssay Description:50% reduction in myeloperoxidase secretion from human PMNs mediated by 100 nM C5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50066481((S)-2-Acetylamino-N-[(5S,11R,14S,17R,19aS)-17-cycl...)
Affinity DataIC50: 280nMAssay Description:50% reduction in binding of [125I]C5a to human polymorphonuclear cells (PMNs)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed