BDBM50065785 2-Methyl-quinolin-8-ol::CHEMBL316892

SMILES Cc1ccc2cccc(O)c2n1

InChI Key InChIKey=NBYLBWHHTUWMER-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50065785   

TargetMethionine aminopeptidase 2(Human)
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50065785(2-Methyl-quinolin-8-ol | CHEMBL316892)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human methionine aminopeptidase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50065785(2-Methyl-quinolin-8-ol | CHEMBL316892)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human methionine aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50065785(2-Methyl-quinolin-8-ol | CHEMBL316892)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro anti-HIV integrase activity against 3' processing of target plasmid.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50065785(2-Methyl-quinolin-8-ol | CHEMBL316892)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro anti-HIV integrase activity against integration (strand transfer) of target plasmid.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065785(2-Methyl-quinolin-8-ol | CHEMBL316892)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Clostridium botulinum BoNT/A LC expressed in Escherichia coli assessed as cleavage of SNAPtide preincubated for 5 mins followed by SNAP...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50065785(2-Methyl-quinolin-8-ol | CHEMBL316892)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant full length human His-tagged methionine aminopeptidase 1 expressed in Escherichia coli BL21(DE3) using methionylprolyl-p-ni...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50065785(2-Methyl-quinolin-8-ol | CHEMBL316892)
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of recombinant full length human N-terminal GST/His6-tagged methionine aminopeptidase 2 expressed in baculovirus infected sf9 cells using ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50065785(2-Methyl-quinolin-8-ol | CHEMBL316892)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of protease activity of recombinant full length Clostridium botulinum Hall BoNT/A light chain using SNAP-25 peptide (187 to 203 residues) ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50065785(2-Methyl-quinolin-8-ol | CHEMBL316892)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 integrase 3' processing activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Freie University Berlin

Curated by ChEMBL
LigandPNGBDBM50065785(2-Methyl-quinolin-8-ol | CHEMBL316892)
Affinity DataIC50: 2.74E+5nMAssay Description:Inhibition of C-terminal 6His-tagged full length NDM-1 (unknown origin) expressed in Escherichia coli BL21-DE3 using nitrocefin as substrate incubate...More data for this Ligand-Target Pair
In DepthDetails
PubMed