BDBM50065400 (R)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonylamino-3-thiophen-2-yl-propionamide::CHEMBL88895

SMILES CS(=O)(=O)N[C@H](Cc1cccs1)C(=O)N[C@@H](Cc1ccccc1)C=O

InChI Key InChIKey=MRAGOGINUXYQRY-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50065400   

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065400((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonyl...)
Affinity DataIC50: 300nMAssay Description:Inhibition of intracellular Calpain-I receptor using intact cell assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065400((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonyl...)
Affinity DataKi:  11nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065400((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonyl...)
Affinity DataKi:  11nMAssay Description:Inhibitory activity against Calpain-II receptor in porcine kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065400((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-2-methanesulfonyl...)
Affinity DataKi:  23nMAssay Description:Inhibitory activity against cathepsin B receptor in human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed