BDBM50065299 4-[4-(5-Bromo-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-phenyl]-piperazine-1-carbaldehyde::4-{4-[5-Bromo-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-phenyl}-piperazine-1-carbaldehyde::CHEMBL88405

SMILES Brc1ccc2NC(=O)\C(=C/c3ccc(cc3)N3CCN(CC3)C=O)c2c1

InChI Key InChIKey=BWIHZZBWTTUUMW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50065299   

LigandPNGBDBM50065299(4-{4-[5-Bromo-2-oxo-1,2-dihydro-indol-(3Z)-ylidene...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against vascular endothelial growth factor receptor 2 (FLK1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Sugen

Curated by ChEMBL
LigandPNGBDBM50065299(4-{4-[5-Bromo-2-oxo-1,2-dihydro-indol-(3Z)-ylidene...)
Affinity DataIC50: 5.00E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50065299(4-{4-[5-Bromo-2-oxo-1,2-dihydro-indol-(3Z)-ylidene...)
Affinity DataIC50: 5.00E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50065299(4-{4-[5-Bromo-2-oxo-1,2-dihydro-indol-(3Z)-ylidene...)
Affinity DataIC50: 5.00E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50065299(4-{4-[5-Bromo-2-oxo-1,2-dihydro-indol-(3Z)-ylidene...)
Affinity DataIC50: 1.38E+4nMAssay Description:Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Sugen

Curated by ChEMBL
LigandPNGBDBM50065299(4-{4-[5-Bromo-2-oxo-1,2-dihydro-indol-(3Z)-ylidene...)
Affinity DataIC50: 5.00E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed