BDBM50065255 (R)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol::CHEMBL87169

SMILES OCC1NC(CO)[C@@H](O)C(O)C1O

InChI Key InChIKey=CLVUFWXGNIFGNC-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50065255   

TargetMaltase-glucoamylase(Human)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50065255((R)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol |...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity measured against alpha-glucosidase of rice by colorimetric assay using the D-glucose oxidase-peroxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50065255((R)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol |...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity measured against alpha-glucosidase of rat liver lysosomal by colorimetric assay using the D-glucose oxidase-peroxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50065255((R)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol |...)
Affinity DataIC50: 800nMAssay Description:Inhibitory activity measured against alpha-glucosidase of rat intestinal sucrase by colorimetric assay using the D-glucose oxidase-peroxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50065255((R)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol |...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity measured against alpha-L-fucosidase of rat epididymis by colorimetric assay using the D-glucose oxidase-peroxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50065255((R)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol |...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibitory activity measured against alpha-L-fucosidase of bovine epididymis by colorimetric assay using the D-glucose oxidase-peroxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50065255((R)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol |...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibitory activity measured against alpha-galactosidase of coffee bean by colorimetric assay using the D-glucose oxidase-peroxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50065255((R)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol |...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity measured against alpha-glucosidase of rat intestinal maltase by colorimetric assay using the D-glucose oxidase-peroxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetTrehalase(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50065255((R)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol |...)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibitory activity measured against trehalase of porcine kidney by colorimetric assay using the D-glucose oxidase-peroxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetMaltase-glucoamylase(Human)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50065255((R)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol |...)
Affinity DataKi:  6.90E+3nMAssay Description:Compound was tested for binding affinity against alpha-glucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed