BDBM50064463 CHEMBL3401177

SMILES Fc1ccc(cc1)-n1ccc2nc(COc3ccccc3)cn2c1=O

InChI Key InChIKey=SCXUQPKHWUFDNI-UHFFFAOYSA-N

Data  1 IC50  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50064463   

TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064463(CHEMBL3401177)
Affinity DataEC50:  309nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064463(CHEMBL3401177)
Affinity DataIC50: 630nMAssay Description:Negative allosteric modulation at mGluR3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064463(CHEMBL3401177)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064463(CHEMBL3401177)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064463(CHEMBL3401177)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064463(CHEMBL3401177)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064463(CHEMBL3401177)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064463(CHEMBL3401177)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064463(CHEMBL3401177)
Affinity DataEC50:  310nMAssay Description:Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed