BDBM50063708 7-Fluoro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazin-4-one::CHEMBL10435

SMILES Fc1ccc2c(c1)nc(Nc1ccccc1I)oc2=O

InChI Key InChIKey=LFBLTYBFHNMNLH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063708   

TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063708(7-Fluoro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50: 2.80E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063708(7-Fluoro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063708(7-Fluoro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration of compound required to inhibit 50% trypsin derived from bovine pancreasMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed