BDBM50063544 1-(6-(methylthio)naphthalen-2-yl)propan-2-amine::1-Methyl-2-(4-methylsulfanyl-phenyl)-ethylamine::2-Amino-1-(4-methylthiophenyl)propane::CHEMBL6467

SMILES CSc1ccc(CC(C)N)cc1

InChI Key InChIKey=OLEWMKVPSUCNLG-UHFFFAOYSA-N

Data  2 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50063544   

TargetTransporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063544(1-Methyl-2-(4-methylsulfanyl-phenyl)-ethylamine | ...)
Affinity DataIC50: 2.38E+3nMAssay Description:Compound was tested for the ability to inhibit [3H]norepinephrine binding to Norepinephrine transporter in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063544(1-Methyl-2-(4-methylsulfanyl-phenyl)-ethylamine | ...)
Affinity DataIC50: 74nMAssay Description:Activity towards Serotonin transporter was determined by the ability to inhibit [3H]5-HT uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50063544(1-Methyl-2-(4-methylsulfanyl-phenyl)-ethylamine | ...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspensionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063544(1-Methyl-2-(4-methylsulfanyl-phenyl)-ethylamine | ...)
Affinity DataIC50: 207nMAssay Description:Inhibition of [3H]5-HT reuptake at rat SERT expressed in HEK293 cells after 2 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50063544(1-Methyl-2-(4-methylsulfanyl-phenyl)-ethylamine | ...)
Affinity DataIC50: 74nMAssay Description:Inhibition of [3H]5-HT uptake at SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50063544(1-Methyl-2-(4-methylsulfanyl-phenyl)-ethylamine | ...)
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of human noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50063544(1-Methyl-2-(4-methylsulfanyl-phenyl)-ethylamine | ...)
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of human dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063544(1-Methyl-2-(4-methylsulfanyl-phenyl)-ethylamine | ...)
Affinity DataIC50: 74nMAssay Description:Inhibition of [3H]5-HT uptake at SERT in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50063544(1-Methyl-2-(4-methylsulfanyl-phenyl)-ethylamine | ...)
Affinity DataIC50: 200nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50063544(1-Methyl-2-(4-methylsulfanyl-phenyl)-ethylamine | ...)
Affinity DataKi:  250nMAssay Description:Inhibition of MAOA in rat brain mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50063544(1-Methyl-2-(4-methylsulfanyl-phenyl)-ethylamine | ...)
Affinity DataKi:  450nMAssay Description:Inhibition of [3H]5-HT uptake at human SERT expressed in HEK293 cells after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed