BDBM50062654 2-Phenylamino-4-trifluoromethyl-pyrimidine-5-carboxylic acid (3,5-dichloro-phenyl)-amide::CHEMBL134776

SMILES FC(F)(F)c1nc(Nc2ccccc2)ncc1C(=O)Nc1cc(Cl)cc(Cl)c1

InChI Key InChIKey=WNQPQTJPJTYUKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50062654   

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062654(2-Phenylamino-4-trifluoromethyl-pyrimidine-5-carbo...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclic AMP-dependent transcription factor ATF-1(Human)
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062654(2-Phenylamino-4-trifluoromethyl-pyrimidine-5-carbo...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed