BDBM50061907 (+/-)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid[(+/-)-m-nicotinylbenzoylalanine]::2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid::CHEMBL23983::meta-nitrobenzoyl)alanine

SMILES NC(CC(=O)c1cccc(c1)[N+]([O-])=O)C(O)=O

InChI Key InChIKey=KBJZPNMDKSNLIZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50061907   

TargetKynurenine 3-monooxygenase(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50061907(meta-nitrobenzoyl)alanine | 2-Amino-4-(3-nitro-phe...)
Affinity DataIC50: 774nMAssay Description:Inhibition of rat kidney Kynurenine 3-hydroxylase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50061907(meta-nitrobenzoyl)alanine | 2-Amino-4-(3-nitro-phe...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50061907(meta-nitrobenzoyl)alanine | 2-Amino-4-(3-nitro-phe...)
Affinity DataIC50: 900nMAssay Description:Inhibition of mouse KMOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50061907(meta-nitrobenzoyl)alanine | 2-Amino-4-(3-nitro-phe...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human KMOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50061907(meta-nitrobenzoyl)alanine | 2-Amino-4-(3-nitro-phe...)
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibitory activity against kynurenine 3-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetKynureninase(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50061907(meta-nitrobenzoyl)alanine | 2-Amino-4-(3-nitro-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Ability to inhibit kynureninase was determined in a competitive inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50061907(meta-nitrobenzoyl)alanine | 2-Amino-4-(3-nitro-phe...)
Affinity DataIC50: 900nMAssay Description:Ability to inhibit kynurenine-3-hydroxylase was determined in a competitive inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50061907(meta-nitrobenzoyl)alanine | 2-Amino-4-(3-nitro-phe...)
Affinity DataIC50: 900nMAssay Description:Inhibition of rat liver KMO using [3,5-3H]-kynurenine substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed