BDBM50061899 2',5'-Dimethyl-3'-(phenylmethyl)spiro[cyclopentane1,7'(8'H)-[2H]imidazol[1,2-a]pyrzolo[4,3-e]pyrimidin]-4'-(5'H)-one::CHEMBL137400

SMILES CN1C2=NC3(CCCC3)CN2c2nn(C)c(Cc3ccccc3)c2C1=O

InChI Key InChIKey=FDOVMJSEGUQXQX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061899   

TargetPhosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061899(2',5'-Dimethyl-3'-(phenylmethyl)spiro[cyclopentane...)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of Phosphodiesterase 3 from bovine heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061899(2',5'-Dimethyl-3'-(phenylmethyl)spiro[cyclopentane...)
Affinity DataIC50: 75nMAssay Description:Inhibition of phosphodiesterase 5 from bovine lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061899(2',5'-Dimethyl-3'-(phenylmethyl)spiro[cyclopentane...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Phosphodiesterase 2 from bovine adrenal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed