BDBM50061882 3-[Bis-(4-fluoro-phenyl)-methoxy]-8-(4-fluoro-benzyl)-8-aza-bicyclo[3.2.1]octane::CHEMBL11768

SMILES Fc1ccc(CN2C3CCC2CC(C3)OC(c2ccc(F)cc2)c2ccc(F)cc2)cc1

InChI Key

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50061882   

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061882(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-(4-fluoro-benz...)
Affinity DataKi:  95.6nMAssay Description:Displacement of [3H]WIN-35428 from the dopamine transporter in rat caudate putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061882(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-(4-fluoro-benz...)
Affinity DataKi:  96nMAssay Description:Displacement of [3H]WIN-35 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061882(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-(4-fluoro-benz...)
Affinity DataKi:  200nMAssay Description:In vitro inhibition of dopamine uptake in rat tissue, was determined using [3H]DAU as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061882(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-(4-fluoro-benz...)
Affinity DataKi:  611nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M1 sites of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061882(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-(4-fluoro-benz...)
Affinity DataKi:  1.54E+3nMAssay Description:Compound is tested for displacement of [3H]pirenzepine at Metabotropic glutamate receptor 1 in Rat brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed