BDBM50061706 (1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]-acetonitrile::CHEMBL344892

SMILES CO\N=C(/C#N)C12CCN(CC1)C2

InChI Key InChIKey=LRXMLERJAJTUBK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50061706   

TargetMuscarinic acetylcholine receptor M1(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061706((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...)
Affinity DataIC50: 1.65E+3nMAssay Description:In vitro affinity against human Muscarinic acetylcholine receptor M1 using quinuclidynyl benzylate (QNB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061706((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...)
Affinity DataIC50: 240nMAssay Description:In vitro affinity is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061706((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...)
Affinity DataIC50: 495nMAssay Description:In vitro affinity is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor M4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061706((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...)
Affinity DataIC50: 300nMAssay Description:In vitro affinity is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50061706((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...)
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of oxotremorine-M (OXO-M) binding to muscarinic receptors of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2018
Entry Details

LigandPNGBDBM50061706((1-Aza-bicyclo[2.2.1]hept-4-yl)-[(Z)-methoxyimino]...)
Affinity DataIC50: 1.95E+3nMAssay Description:In vitro inhibition of [3H]quinuclidinyl benzilate (QNB) binding to muscarinic receptors of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2018
Entry Details