BDBM50060922 CHEMBL3394769

SMILES [#8]-[#6]-c1ccc(-c2ccc(-[#8])cc2)c(\[#6](=[#6]-2/[#6]=[#6]-[#6](=O)-[#6]=[#6]-2)-c2ccc(-[#8])cc2)c1C#Cc1ccc(-[#8])cc1

InChI Key InChIKey=NDBNJHMPBSPDSP-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50060922   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Catholic University of Daegu

Curated by ChEMBL
LigandPNGBDBM50060922(CHEMBL3394769)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human recombinant PTP1B using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50060922(CHEMBL3394769)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Catholic University of Daegu

Curated by ChEMBL
LigandPNGBDBM50060922(CHEMBL3394769)
Affinity DataKi:  3.00E+3nMAssay Description:Mixed-competitive inhibition of human recombinant PTP1B using p-nitrophenylphosphate as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed