BDBM50060717 6-Bromo-5-[(3,4,5-trimethoxy-phenylamino)-methyl]-thieno[2,3-d]pyrimidine-2,4-diamine::CHEMBL331682

SMILES COc1cc(NCc2c(Br)sc3nc(N)nc(N)c23)cc(OC)c1OC

InChI Key InChIKey=VMSSMKPLAXEQHX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50060717   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060717(6-Bromo-5-[(3,4,5-trimethoxy-phenylamino)-methyl]-...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060717(6-Bromo-5-[(3,4,5-trimethoxy-phenylamino)-methyl]-...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of Pneumocystis carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060717(6-Bromo-5-[(3,4,5-trimethoxy-phenylamino)-methyl]-...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed