BDBM50060713 6-Bromo-5-{[methyl-(3,4,5-trimethoxy-phenyl)-amino]-methyl}-thieno[2,3-d]pyrimidine-2,4-diamine::CHEMBL122214

SMILES COc1cc(cc(OC)c1OC)N(C)Cc1c(Br)sc2nc(N)nc(N)c12

InChI Key InChIKey=HPGJTMPJCSSCEX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50060713   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060713(6-Bromo-5-{[methyl-(3,4,5-trimethoxy-phenyl)-amino...)
Affinity DataIC50: 1.27E+5nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060713(6-Bromo-5-{[methyl-(3,4,5-trimethoxy-phenyl)-amino...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of Pneumocystis carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50060713(6-Bromo-5-{[methyl-(3,4,5-trimethoxy-phenyl)-amino...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed