BDBM50060667 CHEMBL3394695

SMILES Cc1nc(sc1C(=O)NCc1ccccn1)-n1cnn(Cc2ccc(cc2)C(F)(F)F)c1=O

InChI Key InChIKey=MBZKEYVPSVQGTM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50060667   

TargetAcyl-CoA desaturase 1(Mouse)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060667(CHEMBL3394695)
Affinity DataIC50: 14nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060667(CHEMBL3394695)
Affinity DataIC50: 227nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed