BDBM50060449 (Z)-(R)-7-[(3R,4S,7S)-6,6-Dimethyl-2-(4-phenylazo-benzenesulfonylamino)-bicyclo[3.1.1]hept-3-yl]-hept-5-enoic acid::7-[6,6-Dimethyl-2-(4-phenylazo-benzenesulfonylamino)-bicyclo[3.1.1]hept-3-yl]-hept-5-enoic acid::CHEMBL420404

SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NS(=O)(=O)c1ccc(cc1)\N=N\c1ccccc1)[C@@H](C\C=C/CCCC(O)=O)C2

InChI Key InChIKey=ZHCHETZUAKVCKK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50060449   

TargetProstaglandin D2 receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060449(7-[6,6-Dimethyl-2-(4-phenylazo-benzenesulfonylamin...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of cAMP formation evoked by the prostaglandin D2 receptor in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060449(7-[6,6-Dimethyl-2-(4-phenylazo-benzenesulfonylamin...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of [3H]PGD-2 specific binding to Prostaglandin D2 receptor from human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060449(7-[6,6-Dimethyl-2-(4-phenylazo-benzenesulfonylamin...)
Affinity DataIC50: 740nMAssay Description:Inhibition of [3H]- (+)-S-145 specific binding to human platelet membranes in TXA2 receptor (TP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060449(7-[6,6-Dimethyl-2-(4-phenylazo-benzenesulfonylamin...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of cAMP formation by carbacyclin in Prostaglandin I2 receptor (IP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060449(7-[6,6-Dimethyl-2-(4-phenylazo-benzenesulfonylamin...)
Affinity DataIC50: 1.30E+3nMAssay Description:Prostaglandin D2 receptor antagonist activity, evaluated by inhibition of [3H]PGD-2 binding to human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060449(7-[6,6-Dimethyl-2-(4-phenylazo-benzenesulfonylamin...)
Affinity DataIC50: 1.00E+3nMAssay Description:Concentration required to inhibit the PGD-2 evoked cAMP formation in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed