BDBM50060035 4-[(R)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2-sulfonylamino)-propionyl]-piperazine-1-carboxylic acid dimethylamide::CHEMBL107627

SMILES CN(C)C(=O)N1CCN(CC1)C(=O)[C@@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=AMRRXWBRMUATPJ-UHFFFAOYSA-N

Data  10 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50060035   

TargetSerine protease hepsin(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50060035(4-[(R)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2...)
Affinity DataIC50: 6.55E+3nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human Hepsin (R45 to L17 residues) D161E/ R162K double mutant expressed in mouse NS0 cells using Bo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50060035(4-[(R)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Bovine)
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060035(4-[(R)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnionic trypsin(Bovine)
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060035(4-[(R)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2...)
Affinity DataKi:  97nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060035(4-[(R)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibitory activity against Plasmin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasma kallikrein(Human)
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060035(4-[(R)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2...)
Affinity DataKi:  7.30E+3nMAssay Description:Inhibitory activity against Kallikrein (PK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060035(4-[(R)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2...)
Affinity DataKi:  1.35E+4nMAssay Description:Inhibitory activity against Activated protein CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Bovine)
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060035(4-[(R)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50060035(4-[(R)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2...)
Affinity DataKi:  2.80E+4nMAssay Description:Inhibitory activity against UK.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor XII(Human)
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060035(4-[(R)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2...)
Affinity DataKi:  6.10E+4nMAssay Description:Inhibitory activity against Coagulation factor XIIMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTissue-type plasminogen activator(Human)
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060035(4-[(R)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory activity against single-chain tissue-type plasminogen activator (sc-tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-1(Human)
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060035(4-[(R)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory activity against glandular kallikrein (GK)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed