BDBM50059974 7-Methyl-2-m-tolyl-1H-[1,8]naphthyridin-4-one::CHEMBL45620

SMILES Cc1cccc(c1)-c1cc(O)c2ccc(C)nc2n1

InChI Key InChIKey=WHANICGPAJMUTA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059974   

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059974(7-Methyl-2-m-tolyl-1H-[1,8]naphthyridin-4-one | CH...)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50059974(7-Methyl-2-m-tolyl-1H-[1,8]naphthyridin-4-one | CH...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed