BDBM50059967 7-Methyl-2-naphthalen-2-yl-1H-[1,8]naphthyridin-4-one::CHEMBL48779

SMILES Cc1ccc2c(O)cc(nc2n1)-c1ccc2ccccc2c1

InChI Key InChIKey=DLKWDNZHLDGWPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059967   

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059967(7-Methyl-2-naphthalen-2-yl-1H-[1,8]naphthyridin-4-...)
Affinity DataIC50: 5.13E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50059967(7-Methyl-2-naphthalen-2-yl-1H-[1,8]naphthyridin-4-...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed