BDBM50059965 5-Methyl-2-naphthalen-2-yl-1H-[1,8]naphthyridin-4-one::CHEMBL48330

SMILES Cc1ccnc2nc(cc(O)c12)-c1ccc2ccccc2c1

InChI Key InChIKey=QEUHGQVYHUYTFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059965   

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059965(5-Methyl-2-naphthalen-2-yl-1H-[1,8]naphthyridin-4-...)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50059965(5-Methyl-2-naphthalen-2-yl-1H-[1,8]naphthyridin-4-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed