BDBM50059833 4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N-ethyl-benzamide::CHEMBL430851

SMILES CCNC(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1

InChI Key InChIKey=ILKRGFKOTHKFFT-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50059833   

TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50059833(4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataIC50: 345nMAssay Description:Binding affinity for Opioid receptor kappa 1 by the inhibition of binding of [3H]U-69593 in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50059833(4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataIC50: 242nMAssay Description:Binding affinity for Opioid receptor mu 1 by the inhibition of binding of [3H]DAMGO in rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50059833(4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataIC50: 150nMAssay Description:Binding affinity for Opioid receptor delta 1 as inhibition of [3H]DADAL binding to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50059833(4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataEC50:  44nMAssay Description:Agonist activity at human DOR expressed in CHO cells assessed as reduction in ERK1/2 phosphorylation levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed