BDBM50059227 1-Benzyl-4-(5-phenyl-1H-pyrazol-3-yl)-piperidine::CHEMBL25938

SMILES C(N1CCC(CC1)c1cc(n[nH]1)-c1ccccc1)c1ccccc1

InChI Key InChIKey=CEFKCGBMUZVVLI-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50059227   

TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059227(1-Benzyl-4-(5-phenyl-1H-pyrazol-3-yl)-piperidine |...)
Affinity DataKi:  11nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D4 (hD4) receptor stably expressed in HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059227(1-Benzyl-4-(5-phenyl-1H-pyrazol-3-yl)-piperidine |...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059227(1-Benzyl-4-(5-phenyl-1H-pyrazol-3-yl)-piperidine |...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]spiperone from recombinant human D4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059227(1-Benzyl-4-(5-phenyl-1H-pyrazol-3-yl)-piperidine |...)
Affinity DataKi:  66nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D2 stably expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059227(1-Benzyl-4-(5-phenyl-1H-pyrazol-3-yl)-piperidine |...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059227(1-Benzyl-4-(5-phenyl-1H-pyrazol-3-yl)-piperidine |...)
Affinity DataKi:  1.40E+3nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D3 (hD3) receptor stably expressed in HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059227(1-Benzyl-4-(5-phenyl-1H-pyrazol-3-yl)-piperidine |...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D3 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed