BDBM50059221 1-(3-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyrazol-3-yl]-piperidine::CHEMBL78287

SMILES Clc1ccc(cc1)-c1cc([nH]n1)C1CCN(Cc2cccc(Cl)c2)CC1

InChI Key InChIKey=KYOJMOVGLXPOHH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059221   

TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059221(1-(3-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyra...)
Affinity DataKi:  60nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D4 (hD4) receptor stably expressed in HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059221(1-(3-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyra...)
Affinity DataKi:  570nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D2 stably expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059221(1-(3-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyra...)
Affinity DataKi:  4.30E+3nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D3 (hD3) receptor stably expressed in HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed