BDBM50059137 1-[2-Amino-6-(2,6-dichloro-phenyl)-pyrido[2,3-d]pyrimidin-7-yl]-3-ethyl-urea::CHEMBL432738

SMILES CCNC(=O)Nc1nc2nc(N)ncc2cc1-c1c(Cl)cccc1Cl

InChI Key InChIKey=BXEDCNVFSZUBPI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059137   

TargetInsulin receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50059137(1-[2-Amino-6-(2,6-dichloro-phenyl)-pyrido[2,3-d]py...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of insulin receptor (InsR) tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50059137(1-[2-Amino-6-(2,6-dichloro-phenyl)-pyrido[2,3-d]py...)
Affinity DataIC50: 77nMAssay Description:Inhibition of C-src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50059137(1-[2-Amino-6-(2,6-dichloro-phenyl)-pyrido[2,3-d]py...)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr) tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed