BDBM50058935 CHEMBL3358455::US9290476, 79C
SMILES COc1nc2ccc(cc2c(Cl)c1Cc1ccc(cc1)C(F)(F)F)C(O)(c1cnnn1C)c1sc(C)nc1C
InChI Key InChIKey=XWZQGKUMJPPPFZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50058935
Affinity DataKd: 57nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
Affinity DataKd: 0.0240nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
Affinity DataKd: 0.0240nMAssay Description:Binding affinity to human wild type RORgammat ligand binding domain expressed in Escherichia coli by thermofluor assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Modulator activity at GAL4-tagged human RORgammat ligand binding domain expressed HEK293T cells by luciferase reporter gene assayMore data for this Ligand-Target Pair