BDBM50058887 CHEMBL3325742

SMILES OC(c1cncs1)(c1ccncc1)c1ccc2nc(Cl)c(Cc3ccc(Cl)cc3)c(Cl)c2c1

InChI Key InChIKey=IHLATMKKENEVMM-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058887   

TargetNuclear receptor ROR-gamma(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50058887(CHEMBL3325742)
Affinity DataKd:  0.830nMAssay Description:Binding affinity to human wild type RORgammat ligand binding domain expressed in Escherichia coli by thermofluor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50058887(CHEMBL3325742)
Affinity DataIC50: 6.5nMAssay Description:Modulator activity at GAL4-tagged human RORgammat ligand binding domain expressed HEK293T cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed