BDBM50058473 (2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-acetylsulfamoyl]-benzoylsulfamoyl}-benzoylamino)-3-methyl-butyryl]-octahydro-indole-2-carboxylic acid (3,3,3-trifluoro-1-isopropyl-2-oxo-propyl)-amide::CHEMBL265769

SMILES CC(C)C(NC(=O)c1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)c(c1)S(=O)(=O)NC(=O)CSc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C)C(=O)N1[C@@H]2CCCC[C@@H]2C[C@@H]1C(=O)NC(C(C)C)C(=O)C(F)(F)F

InChI Key InChIKey=SQEKFRREQBQUKS-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50058473   

TargetMatrix metalloproteinase-9(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50: 2.40E+4nMAssay Description:The concentration required to achieve 50% inhibition against Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50: 5.80E+4nMAssay Description:The concentration required to achieve 50% inhibition against Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50: 1.90E+4nMAssay Description:The concentration required to achieve 50% inhibition against Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50: 3.80E+4nMAssay Description:The concentration required to achieve 50% inhibition against Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50: 26nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-like elastase family member 2A(Pig)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50: 1.00E+3nMAssay Description:The concentration required to achieve 50% inhibition against pig pancreatic elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058473((2R,3aR,7aR)-1-[2-(4-{4-Chloro-3-[2-(3,5-di-tert-b...)
Affinity DataIC50: 2.00E+3nMAssay Description:The concentration required to achieve 50% inhibition against prolyl endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed