BDBM50056985 CHEMBL3329991

SMILES Cc1[nH]c2ccccc2c1CCNS(=O)(=O)c1ccc(\C=C\C(=O)NO)cc1

InChI Key InChIKey=JMDMVJXTEMLGRO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50056985   

TargetHistone deacetylase(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50056985(CHEMBL3329991)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of HDAC in human HeLa cells nuclear extracts incubated for 30 mins by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Huaihe Hospital of Henan University

Curated by ChEMBL
LigandPNGBDBM50056985(CHEMBL3329991)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Huaihe Hospital of Henan University

Curated by ChEMBL
LigandPNGBDBM50056985(CHEMBL3329991)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Huaihe Hospital of Henan University

Curated by ChEMBL
LigandPNGBDBM50056985(CHEMBL3329991)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Huaihe Hospital of Henan University

Curated by ChEMBL
LigandPNGBDBM50056985(CHEMBL3329991)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed