BDBM50056923 (+)-usnic acid::(9bR)-2,6-diacetyl-3,7,9-trihydroxy-8,9b-dimethyldibenzo[b,d]furan-1(9bH)-one::(R)-usnic acid::CHEMBL367881::d-Usnic acid::d-Usninic acid

SMILES CC(=O)C1C(=O)C=C2Oc3c(c(O)c(C)c(O)c3C(C)=O)[C@@]2(C)C1=O

InChI Key InChIKey=CUCUKLJLRRAKFN-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50056923   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056923((9bR)-2,6-diacetyl-3,7,9-trihydroxy-8,9b-dimethyld...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibitory concentration of compound against disintegration (reversal of strand transfer)of HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056923((9bR)-2,6-diacetyl-3,7,9-trihydroxy-8,9b-dimethyld...)
Affinity DataIC50: 1.24E+5nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 1&2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056923((9bR)-2,6-diacetyl-3,7,9-trihydroxy-8,9b-dimethyld...)
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibitory concentration of compound against 3'-processing of HIV-1 integrase in experiment 1&2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Silla University

Curated by ChEMBL
LigandPNGBDBM50056923((9bR)-2,6-diacetyl-3,7,9-trihydroxy-8,9b-dimethyld...)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50056923((9bR)-2,6-diacetyl-3,7,9-trihydroxy-8,9b-dimethyld...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50056923((9bR)-2,6-diacetyl-3,7,9-trihydroxy-8,9b-dimethyld...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using HPPA as substrate after preincubated for 15 min followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
University of London

Curated by ChEMBL
LigandPNGBDBM50056923((9bR)-2,6-diacetyl-3,7,9-trihydroxy-8,9b-dimethyld...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of Escherichia coli FabI using 2-dodecenoyl-CoA as substrate at pH 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50056923((9bR)-2,6-diacetyl-3,7,9-trihydroxy-8,9b-dimethyld...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed