BDBM50056629 4-cyclopropylmethyl-10,17-dihydroxy-15-[1-(4-phenylphenyl)-(E)-methylidene]-(5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::CHEMBL162048::CHEMBL355188

SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)C(=O)C(C[C@@]35O)=Cc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=DVOIJAPNWLCYFS-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50056629   

TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50056629(CHEMBL162048 | 4-cyclopropylmethyl-10,17-dihydroxy...)
Affinity DataKi:  47nMAssay Description:Binding affinity evaluated by inhibition of binding of [3H]DADLE to delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50056629(CHEMBL162048 | 4-cyclopropylmethyl-10,17-dihydroxy...)
Affinity DataKi:  47nMAssay Description:Binding affinity was determined in a crude membrane preparation from guinea pig brain by displacement of [3H]DPDPE from Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50056629(CHEMBL162048 | 4-cyclopropylmethyl-10,17-dihydroxy...)
Affinity DataKi:  50nMAssay Description:Binding affinity was determined in a crude membrane preparation from guinea pig brain by displacement of [3H]DAMGO from Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50056629(CHEMBL162048 | 4-cyclopropylmethyl-10,17-dihydroxy...)
Affinity DataKi:  75nMAssay Description:Binding affinity was determined in a crude membrane preparation from guinea pig brain by displacement of [3H]DPDPE from Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50056629(CHEMBL162048 | 4-cyclopropylmethyl-10,17-dihydroxy...)
Affinity DataKi:  75nMAssay Description:Binding affinity evaluated by inhibition of binding of [3H]DADLE to delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50056629(CHEMBL162048 | 4-cyclopropylmethyl-10,17-dihydroxy...)
Affinity DataKi:  190nMAssay Description:Binding affinity was determined in a crude membrane preparation from guinea pig brain by displacement of [3H]U-69593 from Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50056629(CHEMBL162048 | 4-cyclopropylmethyl-10,17-dihydroxy...)
Affinity DataKi:  210nMAssay Description:Binding affinity was determined in a crude membrane preparation from guinea pig brain by displacement of [3H]DAMGO from Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50056629(CHEMBL162048 | 4-cyclopropylmethyl-10,17-dihydroxy...)
Affinity DataKi:  400nMAssay Description:Binding affinity was determined in a crude membrane preparation from guinea pig brain by displacement of [3H]U-69593 from Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed