BDBM50056627 4-cyclopropylmethyl-10,17-dihydroxy-15-[1-(2-naphthyl)-(E)-methylidene]-(5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::CHEMBL164577

SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)C(=O)C(C[C@@]35O)=Cc1ccc2ccccc2c1

InChI Key InChIKey=COXHSSWZQBEBOP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056627   

TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50056627(4-cyclopropylmethyl-10,17-dihydroxy-15-[1-(2-napht...)
Affinity DataKi:  23nMAssay Description:Binding affinity was determined in a crude membrane preparation from guinea pig brain by displacement of [3H]DAMGO from Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50056627(4-cyclopropylmethyl-10,17-dihydroxy-15-[1-(2-napht...)
Affinity DataKi:  39nMAssay Description:Binding affinity was determined in a crude membrane preparation from guinea pig brain by displacement of [3H]DPDPE from Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50056627(4-cyclopropylmethyl-10,17-dihydroxy-15-[1-(2-napht...)
Affinity DataKi:  39nMAssay Description:Binding affinity evaluated by inhibition of binding of [3H]DADLE to delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50056627(4-cyclopropylmethyl-10,17-dihydroxy-15-[1-(2-napht...)
Affinity DataKi:  74nMAssay Description:Binding affinity was determined in a crude membrane preparation from guinea pig brain by displacement of [3H]U-69593 from Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed