BDBM50056126 CHEMBL3322141

SMILES CCN(CCC(=O)NCCCNc1c2CCCCc2nc2ccccc12)C1CCCCC1

InChI Key InChIKey=GDXNXPQGVOTDDZ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056126   

TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056126(CHEMBL3322141)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056126(CHEMBL3322141)
Affinity DataIC50: 267nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056126(CHEMBL3322141)
Affinity DataKi:  79nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056126(CHEMBL3322141)
Affinity DataKi:  80nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed