BDBM50056109 CHEMBL3326709

SMILES FC(F)(F)Oc1ccc2oc(=O)c(cc2c1)C(=O)NCCCCCCNc1c2CCCCc2nc2ccccc12

InChI Key InChIKey=QTJIWFKUPQRREG-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50056109   

TargetBeta-secretase 1(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056109(CHEMBL3326709)
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of beta-secretase (unknown origin) using 150 nM Rhodamine-EVNLDAEFK-quencher substrate proteolysis by fluorescence resonance energy transf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056109(CHEMBL3326709)
Affinity DataKi:  18nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056109(CHEMBL3326709)
Affinity DataKi:  60nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed