BDBM50056081 (2R,3R,4S)-1-Dibutylcarbamoylmethyl-4-(2,3-dihydro-benzofuran-6-yl)-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::1-Dibutylcarbamoylmethyl-4-(2,3-dihydro-benzofuran-6-yl)-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL326191

SMILES CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2CCOc2c1

InChI Key InChIKey=AFEYCZJMYZYJSC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056081   

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056081(1-Dibutylcarbamoylmethyl-4-(2,3-dihydro-benzofuran...)
Affinity DataIC50: 1nMAssay Description:Binding affinity towards endothelin A receptor in prolactin secreting rat pituitary cells using [125I]ET1 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056081(1-Dibutylcarbamoylmethyl-4-(2,3-dihydro-benzofuran...)
Affinity DataIC50: 960nMAssay Description:Binding affinity towards endothelin B receptor in porcine cerebellar tissue using [125I]-ET-1 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056081(1-Dibutylcarbamoylmethyl-4-(2,3-dihydro-benzofuran...)
Affinity DataIC50: 960nMAssay Description:Binding affinity against endothelin B receptor in porcine cerebellar tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056081(1-Dibutylcarbamoylmethyl-4-(2,3-dihydro-benzofuran...)
Affinity DataIC50: 1.20nMAssay Description:Binding affinity against endothelin A receptor in MMQ cells in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed