BDBM50056071 (2R,3R,4S)-4-Benzofuran-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::4-Benzofuran-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL112832

SMILES CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2occc2c1

InChI Key InChIKey=CSDXUYVBDBLUJV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50056071   

TargetEndothelin receptor type B(Pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056071(4-Benzofuran-5-yl-1-dibutylcarbamoylmethyl-2-(4-me...)
Affinity DataIC50: 5.10E+3nMAssay Description:Binding affinity towards endothelin B receptor in porcine cerebellar tissue using [125I]-ET-1 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056071(4-Benzofuran-5-yl-1-dibutylcarbamoylmethyl-2-(4-me...)
Affinity DataIC50: 0.5nMAssay Description:Binding affinity towards endothelin A receptor in prolactin secreting rat pituitary cells using [125I]ET1 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056071(4-Benzofuran-5-yl-1-dibutylcarbamoylmethyl-2-(4-me...)
Affinity DataIC50: 5.08E+3nMAssay Description:Binding affinity against endothelin B receptor in porcine cerebellar tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056071(4-Benzofuran-5-yl-1-dibutylcarbamoylmethyl-2-(4-me...)
Affinity DataIC50: 0.480nMAssay Description:Binding affinity against endothelin A receptor in MMQ cells in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056071(4-Benzofuran-5-yl-1-dibutylcarbamoylmethyl-2-(4-me...)
Affinity DataIC50: 0.5nMAssay Description:Ability to displace [125I]ET1 from the rat endothelin A receptor expressed in rat aorta smooth muscle cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed